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doi: 10.1038/s41586-019-1707-0 55 AnandhanADodsonMSchmidlinCJLiuPZhangDD

doi: 10.1136/jim-2021-002062 2 KangPZhangWGJiZHShaoZJLiCY

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Additionally, glutamine contributes to the intermediary metabolism [19] in the synthesis of amino sugars and proteins [20,21,22], promotes insulin secretion from pancreatic beta cells, and is the precursor of key molecules such as the excitatory neurotransmitter glutamate, the inhibitory neurotransmitter -aminobutyrate (GABA), and the antioxidant glutathione (GSH) [1, 23, 24], considered a powerful marker of the cellular redox potential [25, 26]