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A clinical trial involving 42 PD patients (2:1 randomized to NAC or control) demonstrated that a 3-month NAC regimen (50 mg/kg intravenous weekly plus 600 mg oral twice daily, skipping oral doses on infusion days) significantly increased dopamine transporter binding compared with the control group

10.1093/pcp/pcr133 2 AstierJ.KulikA.KoenE.Besson-BardA.BourqueS.JeandrozS.et al

This metabolic reprogramming led to mitochondrial membrane depolarization, increased reactive oxygen species generation, induction of apoptosis, and cell-cycle arrest at the G 2 phase

Research suggests that moderate, consistent dosing is more effective than sporadic high doses

Its unlikely you would have physical symptoms

Best Cooking Methods for Keeping Nutrients Intact Research published in the International Journal of Food Sciences and Nutrition tested several cooking methods with interesting results: Grilling and microwaving: These preserved the highest levels of antioxidant activity