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In both cohorts, subjects treated with CHANTIX had a superior rate of CO-confirmed abstinence during weeks 9 through 12 and 9 through 24 compared to subjects treated with bupropion, nicotine patch and placebo

It comes pre-charged, you puff on the device to activate it

The most frequently reported use motives were to quit combusted tobacco (16.8%) and reduce tobacco smell (15.4%)

PMID: 17234265

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Reducing your intake or abstaining entirely can cause symptoms of withdrawal, which can include intense cravings, irritability, and insomnia