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Although these analyses are not specific to the central nervous system (CNS), they do offer clues to ongoing brain injury pathogenesis, as the increased permeability of the bloodbrain barrier (BBB) after TBI allows for greater exchange of CNS/peripheral solutes, and many of these metabolites are also detected in the brain parenchyma [34]

GHK-Cu is widely used in cosmetic formulations and studied extensively in scientific literature, though regulatory status varies by country and use case (cosmetic versus injectable)

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In many places, it exists in a regulatory gray area, being available for research purposes but not approved for human consumption

doi: 10.1111/j.1471-4159.1992.tb10990.x 95 BazinetRPLayeS

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