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In addition, the increase in palatable food-motivated behaviors induced by ghrelin is prevented by administration of dopamine receptor type 1 and type 2 antagonists [76,78], thus further highlighting the critical role of downstream dopamine signaling

The authors concluded that Hexarelin exerts a short-lasting, positive inotropic effect that appears independent of its growth hormone-releasing activity, supporting a direct cardiac action and motivating further investigation of peptide-based cardiac research

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doi:10.1097/01.aids.0000131354.14408.fb

A previous placebo-controlled study comparing orally administered tablets of phenylephrine or pseudoephedrine vs placebo support the conclusion that pseudoephedrine tablets are effective in reducing nasal congestion , whereas the effect produced by phenylephrine tablets are no different than placebo (Horak et al, 2009)