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Acanthosis Nigricans is not a major skin disease but it is an external manifestation to various internal problems

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GLP-1 medications are also known as GLP-1 receptor agonists (GLP-1 RAs), which imitate the natural GLP-1 hormone, responsible for regulating our blood sugar levels, insulin, and hunger

This is not a direct side effect of the medication itself, but rather a result of losing fat quickly

Case-control study

The most frequently reported adverse events with combination therapy are gastrointestinal symptoms, including nausea, vomiting, and diarrhea, which are primarily attributable to GLP-1 receptor agonists and may occur more often than with SGLT2 inhibitor monotherapy [24, 43]