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Moreover, high eHSP72 levels have been linked to diabetic complications such as ketoacidosis, highlighting the importance of maintaining a finely tuned balance between intracellular and extracellular HSP72 for therapeutic intervention

We next tested the impact of the 5-HTR 2 antagonist ketanserin, injecting male mice with ketanserin (5 mg/kg) 30 minutes before serotonin administration (20 mg/kg) (Figure 6C)

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95% CI, 0.64 to 1.12

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