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Understanding where they fit helps make informed decisions

What research is there to support the health and fitness claims

For wound healing, use 2-3mg daily until healed

Long-term use of metformin, proton pump inhibitors or H2 blockers , which can reduce B12 absorption over years

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A 2019 randomized controlled trial of lipotropic injections (methionine, inositol, choline, B12) versus saline placebo in 120 participants on ad libitum diets found 0.8 kg (1.76 pounds) difference at 12 weeks, not statistically significant (p=0.18) (Karbalay-Doust et al., Journal of Research in Medical Sciences , 2019)