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As can be seen in Figure 1 , patients receiving CET demonstrated significant and large improvements across the domains of Neurocognition, Processing Speed, Cognitive Style, and Social Cognition, after two years of treatment

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Dose-dependent effects of recombinant human insulin-like growth factor (IGF)-I/IGF binding protein-3 complex on overnight growth hormone secretion and insulin sensitivity in type 1 diabetes

Journal of the Royal Society of Medicine

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The appearance of lyophilized powder can vary from a solid, dense puck to a more diffuse powder, but this does not affect the mass