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(2018) for other elements could help to further clarify barrier processes regarding Se and seleno-species

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In cardiac cells, the physical proximity between mitochondria and the sarcoplasmic reticulum (SR, a specific type of ER in heart and skeletal muscle cells) allows the exchange of Ca 2+ in local microdomains, providing rapid Ca 2+ buffering

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Months 1-3: Foundation (As Described Above) The initial quarter establishes protocols and allows for initial cellular adaptation and response assessment