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The review also documented how GCL expression is transcriptionally upregulated by electrophiles through antioxidant response elements (ARE/EpRE) in the GCLC and GCLM promoters establishing the Nrf2/ARE pathway as the master regulator of GSH biosynthetic capacity under stress conditions

Liraglutide demonstrated improved insulin sensitivity within just two weeks of starting treatment 4

thus, it is essential for the inhibition of ferroptosis

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