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COVID-19 and heme oxygenase: novel insight into the disease and potential therapies

The problem is that GLP-1 is rapidly inactivated (half-life of approximately one minute) by the enzyme DPP-4

Shifting the injection to Monday places the trough over the weekend, which may fit better with individual weekly routines

Mela V, Ruiz-Limn P, Balongo M, Motahari Rad H, Subiri-Verdugo A, Gonzalez-Jimenez A, et al

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2000 May;157(5):715-21