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Currently, three Phase III trials are in progress, designed to assess the comparative efficacy of a combination therapy consisting of arhalofenate plus febuxostat 40 mg versus febuxostat monotherapy at 80 mg

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doi: 10.1177/10781552231171114 319 AfsarTRazakSAlmajwalAAl-DisiD

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Following comprehensive evaluations in 20132014, both agencies concluded that available evidence did not support a causal association between these medications and pancreatic cancer

Superiority testing followed a hierarchical order, beginning with the highest Cagrilintide dose versus placebo, using a two-sided 5% significance threshold