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et al.: Triple-Hormone-Receptor Agonist Retatrutide for Obesity A Phase 2 Trial

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The study did not find similar optic nerve risks with drugs such as Mounjaro or Zepbound, which use a different mechanism

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In a controlled colesevelam trial in 30 patients with IBS-D, colesevelam did not alter mucosal permeability (179)

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Notably, AzaA8 achieved these benefits without the need for fatty acid derivatization or other extensive modifications beyond the aza-substitution

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Available from: 2 Knezevic NN, Mandalia S, Raasch J, Knezevic I, Candido KD

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