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Mutation can change the binding site of imatinib to the BCRABL (break point cluster regionAbelson murine leukaemia viral oncogene homolog 1) gene, thereby inhibiting the activity of imatinib amongst patients who have chronic myeloid leukaemia [87, 88]

2010, doi: 10.1016/j.rbmo.2010.03.008

All purified RNA samples were diluted and adjusted to 400 ng/l to ensure equal amounts of cDNA template for quantification of mRNA abundance

Indeed, WT and Myd88 / , but not Nlrp3 / macrophages, presented increased tricarboxylate transport protein (Slc25a1) mRNA, a citrate carrier protein necessary for the generation of mitochondrial oxidative stress upon uric acid stimulation 63,64 (Fig

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Carnitine status can be assessed by measuring circulating carnitine levels