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Age (Dordr) (2012) 35:167590.10.1007/s11357-012-9470-2 132 GrammatopoulosTNOuteiroTFHymanBTStandaertDG

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Preclinical studies demonstrate that DSIP can alter pain threshold responses, with observed effects that are not reversed by opioid receptor antagonists such as naloxone, suggesting involvement of non-opioid or indirect neuromodulatory pathways [7]

Apply serum first, then a conductive gel layer

J Clin Diagn Res