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rather, it constitutes a metabolically active biochemical processing center that enzymatically biotransforms xenobiotics and endogenous toxins through highly regulated, pathway-specific metabolic processes

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KPV is a naturally occurring peptide fragment used for research purposes

FIGURE 8 The aforementioned abnormalities at the molecular level (downregulation of the Nrf2/HO-1 axis and GPX4) and subcellular structural level (neuronal somata and mitochondrial impairment) were consistent with the GSH metabolism perturbations identified by multi-omics analyses, collectively reflecting oxidative stress-associated damage in the hippocampus during SAE

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