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It can be depleted quickly if a person is sick, has been working out vigorously, heavily drinking or smoking in turn, making you susceptible to illness

Apply these at different times of day, such as copper peptides in the morning and retinoids at night

"The role of hyperhomocysteinemia as well as folate, vitamin B(6) and B(12) deficiencies in osteoporosis: a systematic review"

The comparison to vitamin C and retinoic acid (70% vs 50% vs 40% collagen improvement) is cited widely but comes from a single study

S2CID 29422959

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